Workflow catalog

Comprehensive scientific
workflow platform

NuHelix AI orchestrates validated, reproducible bioinformatics workflows — from raw reads to publication-ready figures — powered by the tools your lab already trusts.

8+
Workflow categories
30+
Supported tools
6
Knowledge sources
100%
Reproducible outputs
Workflow categories

Every stage of your pipeline

From raw QC to pathway enrichment — each workflow category runs validated tools in the correct order, with full provenance tracking.

Quality Control

Assess raw sequencing data quality, trim adapters, and filter low-quality reads before downstream analysis.

FastQCMultiQCTrimmomaticfastp
QCNGSPreprocessing
See documentation

Alignment & Mapping

Align short or long reads to reference genomes using splice-aware and standard alignment algorithms.

STARHISAT2BWAminimap2
AlignmentGenomeShort-read
See documentation

Quantification

Generate read count matrices and transcript abundance estimates from aligned or raw reads.

featureCountsSalmonkallistoHTSeq
CountsExpressionPseudoalignment
See documentation

Differential Expression

Identify statistically significant changes in gene expression between experimental conditions.

DESeq2edgeRlimmaDEXSeq
DE AnalysisStatisticsR
See documentation

Single-Cell Analysis

Cluster, annotate, and interpret single-cell transcriptomic data from diverse tissue types.

SeuratScanpyscranMonocle3
scRNA-seqClusteringUMAP
See documentation

Variant Analysis

Detect and annotate SNPs, indels, and structural variants from whole-genome or exome data.

GATKbcftoolsFreeBayesDeepVariant
SNVIndelGermline
See documentation

Pathway Enrichment

Assess biological pathway activity and gene ontology enrichment from ranked gene lists.

GSEAclusterProfilerEnrichrfgsea
PathwaysGOKEGG
See documentation

Visualization & Reporting

Generate publication-quality figures, interactive plots, and structured analysis reports.

ggplot2matplotlibseabornplotly
FiguresPublicationExport
See documentation
Knowledge sources

Grounded in curated biological databases

Annotations, pathway data, and reference assemblies are sourced from trusted public databases and kept up to date.

GenomicsActive

NCBI / GenBank

Nucleotide sequences, gene records, and reference assemblies from NCBI.

AnnotationActive

Ensembl

Gene annotation, comparative genomics, and regulatory features for vertebrates.

BrowserActive

UCSC Genome Browser

Genome assemblies, tracks, and conservation data for human and model organisms.

PathwaysActive

KEGG

Pathway maps, disease associations, and biochemical reaction networks.

OntologyActive

Gene Ontology (GO)

Structured biological vocabulary for gene function annotation and enrichment.

ReactionsActive

Reactome

Curated human biological pathways with experimentally validated reactions.

How it works

From question to publishable output

The platform bridges your research intent and validated computational tools — no scripting, no environment setup.

1

You describe what you need

Plain language input

2

Workflow is selected and validated

Structured plan preview

3

Tools run on cloud infrastructure

Real compute, real tools

4

Results, figures, and report generated

Full provenance attached

Missing a workflow?

Request a workflow or tool

Don't see the analysis you need? Submit a workflow request and our team will prioritize adding it to the catalog.